Advancing Trypanosoma Parasite Research Through High-Resolution and Big-Data Methodologies

Silva Pereira S*, Brás D, Porqueddu T, Nascimento A, De Niz M* Investigation of Trypanosoma-induced vascular damage sheds insights into Trypanosoma vivax sequestration (2023) The Cell Surface 10: 100113

Silva Pereira S¶, De Niz M¶, Serre K, Ouarné M, Franco CA, Figueiredo LM Immunopathology and Trypanosoma congolense parasite sequestration cause severe cerebral trypanosomiasis (2022) eLife 11 e77440

Silva Pereira S*, Mathenge K, Masiga D, Jackson AP Transcriptomic profiling of Trypanosoma congolense mouthpart parasites from naturally infected flies (2022) Parasites & Vectors 15:152

Viegas I, Pereira de Macedo J, Serra L, De Niz M, Temporão A, Silva Pereira S, Mirza A, Bergstom E, Rodrigues JA, Aresta-Branco F, Jaffrey S, Figueiredo LM (2022) N6-methyladenosine in poly(A) tails stabilize VSG transcripts Nature 604, 362-270

Silva Pereira S, Neto K, Duffy CW, Richards P, Noyes H, Ogugo M, André MR, Bengaly Z, Kemp S, Teixeira MMG, Machado RZ, Jackson AP (2020) Variant antigen diversity in Trypanosoma vivax is not driven by recombination. Nature Communications 11:844

Silva Pereira S*, Heap J, Jones AR, Jackson AP (2019) VAPPER: Highthroughput Variant Antigen Profiling in African trypanosomes of Livestock. GigaScience 8(9): giz091

Ebenezer TE, Zoltner M, Burrell A, Nenarokova A, Novák Vanclová AMG, Prasad B, (...) Silva Pereira S, Jackson AP, Devos DP, Lukeš J, Lebert M, Vaughan S, Hampl V, Carrington M, Ginger ML, Dacks JB, Kelly S, Field MC (2019) Transcriptome, proteome and draft genome of Euglena gracilis. BMC Biology 17(1): 11

Silva Pereira S*, Casas-Sánchez A, Haines LR, Ogugo M, Absolomon K, Sanders M, Kemp S, Acosta-Serrano A, Noyes H, Berriman M, Jackson AP (2018) Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data with a set of universal protein motifs. Genome Research 28: 1383-1394

Abbas AH¶, Silva Pereira, S¶ *, D’Archivio S, Wickstead B, Morrison LJ, Hall N, Hertz-Fowler C, Darby AC, Jackson, AP (2018) The structure of a conserved telomeric region in Trypanosoma congolense associated with Variant Surface Glycoprotein loci. Genome Biology and Evolution 10(9): 2458–2473 (¶ joint first authorship)

Silva Pereira S* & Jackson AP (2018) UDP-glycosyltransferase genes in trypanosomatid genomes have diversified independently to meet the distinct developmental needs of parasite lineages. BMC Evolutionary Biology 18(31)

Bhattacharyya T, Ayandeh A, Falconar AK, Sundar S, El-Safi S, Gripenberg MA, (…) Silva Pereira S, Boelaert M, Mertens P, Miles MA (2014) IgG1 as a Potential Biomarker of Post-Chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test. PLOS Neglected Tropical Diseases e3273

Research Articles

Kent RS¶, Briggs EM¶, Colon BL¶, Alvarez C¶, Silva Pereira S¶, De Niz M¶ (2022) Paving the way: contributions of big data to Apicomplexan and Kinetoplastid research. Frontiers in Cellular and Infection Microbiology 12:900878.

Silva Pereira S, Jackson AP, Figueiredo LM (2021) Evolution of the Variant Surface Glycoprotein superfamily in African trypanosomes. Trends in Parasitology doi: 10.1016/

Silva Pereira S, Trindade S, De Niz M, Figueiredo LM (2019) Tissue Tropism in Parasitic Diseases. Open Biology 9(5): 190036

Review Articles

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